Reaction of oxiranes with cyclodextrins under high-energy ball-milling conditions

• László Jicsinszky,
• Federica Calsolaro,
• Katia Martina,
• Fabio Bucciol,
• Maela Manzoli and
• Giancarlo Cravotto

Beilstein J. Org. Chem. 2019, 15, 1448–1459, doi:10.3762/bjoc.15.145

• have different complexation properties to those of their classically prepared analogues. Keywords: crosslinked cyclodextrin polymers; (2-hydroxy)propylcyclodextrin; mechanochemistry; nucleophile reaction; planetary ball mill; solventless synthesis; Introduction The derivatisation of natural

Organobase-catalyzed three-component reactions for the synthesis of 4H-2-aminopyrans, condensed pyrans and polysubstituted benzenes

• Moustafa Sherief Moustafa,
• Saleh Mohammed Al-Mousawi,
• Maghraby Ali Selim,
• Ahmed Mohamed Mosallam and
• Mohamed Hilmy Elnagdi

Beilstein J. Org. Chem. 2014, 10, 141–149, doi:10.3762/bjoc.10.11

• nucleophile, reaction of DEAD with 7a readily took place and the substituted phthalate diester 37a was obtained in 80% yield. The structure of 37a was determined by X-ray crystallographic analysis (Scheme 10 and Figure 11). In a similar fashion, DEAD was observed to react with the p-nitro- and p-chloro